Breast Hamartoma with Unusual Imaging Features.
Palwasha Gul1, Jonathan James1, Mohamad Hajaj1
1Nottingham University Hospitals NHS Trust - City Campus: Nottingham City Hospital, Nottingham, Nottinghamshire UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
Breast hamartomas are rare benign tumors. While typically identified through imaging, atypical presentations necessitate biopsy and multidisciplinary discussion to rule out malignancy.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Breast hamartomas are uncommon benign neoplasms characterized by a mixture of mature adipose and fibrous tissue, along with epithelial elements.
- Their exact etiology and pathogenesis remain incompletely understood, though they predominantly affect middle-aged women.
Observation:
- This report details two cases of breast hamartoma in women aged 51 and 61.
- Both cases presented with imaging findings suggestive of hamartoma, but with internal distortions raising suspicion for malignancy.
Findings:
- Atypical imaging features within breast hamartomas can mimic malignancy, necessitating further investigation.
- Core biopsy and multidisciplinary team (MDT) review are essential for accurate diagnosis and management of such cases.
Implications:
- While most hamartomas have characteristic benign imaging, atypical presentations require biopsy to exclude breast carcinoma.
- Radiological-pathological concordance, achieved through MDT discussion, is crucial for managing ambiguous cases of breast hamartoma.
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