Related Experiment Video
Updated: Jul 13, 2026
06:38
A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
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An Extremely Rare Anomaly: Unveiling Renal Vein-Originated Leiomyosarcoma
Jihane El Hamzaoui1,2, Ali Kada1,2, Imane El Messaoudi1,2
1Department of General Surgery C, Centre Hospitalier Ibn Sina, Rabat, Morocco.
Case Reports in Surgery
|June 11, 2025
Summary
Primary leiomyosarcoma (LMS) of the renal vein is exceptionally rare. This case highlights the diagnostic challenges and emphasizes radical surgical resection as the primary treatment for this aggressive soft tissue sarcoma.
Area of Science:
- Oncology
- Vascular Surgery
- Pathology
Background:
- Leiomyosarcoma (LMS) is a rare soft tissue sarcoma, with angiogenic LMS predominantly affecting the inferior vena cava (IVC).
- Primary LMS originating from the renal vein is exceedingly rare, posing diagnostic and therapeutic challenges.
Observation:
- A 73-year-old woman presented with intermittent left flank pain, found to have a large left latero-aortic mass.
- Exploratory laparotomy revealed a multinodular tumor at the left renal hilum, requiring en bloc resection with left nephrectomy.
Findings:
- Pathological examination confirmed a grade 2 leiomyosarcoma of the left renal vein.
- The patient experienced a good postoperative recovery without immediate complications.
Implications:
- Renal vein LMS is a rare entity requiring a high index of suspicion due to nonspecific symptoms and imaging.
- Radical surgical resection is the cornerstone of treatment, offering the best chance for improved outcomes.
- Prognosis remains guarded, particularly for larger, high-grade tumors, necessitating further research into optimal adjuvant therapies.
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