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03:37
Application of Robot-assisted Pancreaticobiliary Junction Resection in Benign Duodenal Tumors
Published on: December 20, 2024
492
Risk factors for recurrence after endoscopic papillectomy in ampullary adenomas: a retrospective case-control study
Kun Liu1, Yuhang Zhuang1, Ningjing Gao2
1Department of Gastroenterology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing Medical University, Nanjing, Jiangsu, China.
Therapeutic Advances in Gastroenterology
|June 11, 2025
Summary
Endoscopic papillectomy (EP) effectively treats ampullary adenomas, but recurrence is a concern. Familial adenomatous polyposis (FAP), pancreaticobiliary (PB) subtype, and high-grade dysplasia (HGD) increase recurrence risk.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Oncology
Background:
- Endoscopic papillectomy (EP) is a minimally invasive treatment for ampullary adenomas.
- Concerns exist regarding incomplete resection and recurrence rates following EP.
Purpose of the Study:
- To evaluate the efficacy of EP for ampullary adenomas.
- To identify risk factors associated with tumor recurrence after EP.
Main Methods:
- Retrospective case-control study of 137 patients undergoing EP.
- Analysis of recurrence rates and risk factors using Cox proportional hazards models.
Main Results:
- A 15.3% recurrence rate was observed among patients with complete resection.
- Familial adenomatous polyposis (FAP), pancreaticobiliary (PB) subtype, and high-grade dysplasia (HGD) were significant risk factors for recurrence.
Conclusions:
- EP is effective for ampullary adenomas, but recurrence is a significant concern.
- FAP, PB subtype, and HGD are key risk factors for recurrence, necessitating close monitoring.
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