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Bacteremia after upper gastrointestinal endoscopy.

A L Baltch, I Buhac, A Agrawal

    Archives of Internal Medicine
    |May 1, 1977
    PubMed
    Summary
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    Upper gastrointestinal endoscopy can cause transient bacteremia (bacteria in the bloodstream) in 8% of patients. However, this study found no long-term complications associated with this transient bacteremia.

    Area of Science:

    • Microbiology
    • Gastroenterology

    Background:

    • Transient bacteremia is a known risk associated with invasive procedures.
    • Understanding the incidence and implications of bacteremia following upper gastrointestinal endoscopy is crucial for patient safety.

    Purpose of the Study:

    • To determine the incidence of bacteremia following upper gastrointestinal endoscopy.
    • To identify potential risk factors and clinical significance of bacteremia in this context.

    Main Methods:

    • Prospective study involving 200 upper gastrointestinal endoscopies in 193 patients over 24 months.
    • Blood cultures collected pre-procedure, and at 5 and 30 minutes post-procedure.
    • Analysis of bacteremia correlation with patient demographics, procedural factors, and clinical outcomes.

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    Main Results:

    • Bacteremia occurred in 16 patients (8%), with 12 different groups of microorganisms identified.
    • Most positive blood cultures were transient, with a few persisting up to 30 minutes post-procedure.
    • No significant correlation found between bacteremia and patient age, history, biopsy, bleeding, procedure duration, or findings.

    Conclusions:

    • Upper gastrointestinal endoscopy is associated with a low incidence of transient bacteremia.
    • The detected bacteremia did not lead to any observed complications during a 6-month to 2-year follow-up.
    • Routine antibiotic prophylaxis may not be necessary for all patients undergoing upper gastrointestinal endoscopy based on these findings.