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Updated: Jun 15, 2025

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Transmembrane Protein-184A Interacts with Syndecan-4 and Rab GTPases and Is Required to Maintain VE-Cadherin Levels

Leanna M Altenburg1, Stephanie H Wang1, Grace O Ciabattoni1,2

  • 1Department of Biological Sciences, Lehigh University, Bethlehem, PA 18015, USA.

Cells
|June 11, 2025
PubMed
Summary

Transmembrane protein-184A (TMEM184A) and Syndecan-4 (Sdc4) cooperate in blood vessel repair. TMEM184A has a dual role in cell signaling and trafficking, promoting vascular endothelial cadherin (VE-cad) localization and recovery.

Keywords:
TMEM184AVE-cadherinangiogenesisendothelial cellssyndecan-4

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