Magnetic Resonance Applications to Metabolism
Anna Rushin1, Mario C Chang1, Anthony Giacalone1
1Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, USA.
Abstract:
Magnetic resonance imaging/spectroscopy (MRI/S) is a noninvasive technology used extensively in metabolic research. MRS is used to measure concentrations of specific metabolites, often in specific dynamic processes. MRI provides real-time anatomical and functional imaging capabilities with high spatial resolution. Here, we discuss how MR can be utilized for metabolic flux analysis (MFA) in cells and perfused organs, to study real-time metabolism in ex vivo perfused organs, and to examine in vivo metabolism using perdeuterated substrates with deuterium metabolic imaging and spectroscopy.
Related Concept Videos
Applications Of NMR In Biology
Magnetic Resonance Imaging
Nuclear Magnetic Resonance (NMR): Overview
NMR spectroscopy generates a spectrum where the characteristic absorption frequencies of the sample are...
Atomic Nuclei: Magnetic Resonance
Proteomics
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...


