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Updated: Jun 13, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Photoinduced Copper-Catalyzed Coupling of Acylsilanes with Indoles or Electron-Rich Arenes
Jing Yuan1, Peng-Fei Xia1, Chang-Deng Liu1
1Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang 414006, China.
Abstract:
Although the reactions of electrophilic Fischer-type metal siloxycarbenes catalytically generated in situ from acylsilanes with a single nucleophile have been documented, the coupling of acylsilanes with two nucleophiles remains unexplored. Herein, we demonstrate that acylsilanes can act as effective cationic carbyne equivalents under visible-light-driven copper catalysis, enabling their coupling with diverse indoles or electron-rich arenes. This strategy operates under mild, redox-neutral conditions and exhibits broad functional group compatibility. Furthermore, the protocol provides a versatile platform for synthesizing symmetric aryl(bisindolyl)methanes and unsymmetric triarylmethane derivatives with high efficiency.
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