Functional outcome measures for pediatric upper limb deficiencies with and without prostheses: A systematic review

Holly Cordray1, Miguel Fiandeiro1, Manisha Banala1

  • 1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

Insights

No single outcome measure perfectly assesses pediatric upper limb deficiencies (ULDs). The Assisting Hand Assessment and Assessment of Capacity for Myoelectric Control show promise for observational assessment, while the Child Amputee Prosthetics Project-Functional Status Inventory is a provisional recommendation for questionnaires.

Area of Science:

  • Orthopedics and Rehabilitation
  • Pediatric Health
  • Prosthetics and Assistive Devices

Background:

  • Effective orthopedic care for pediatric upper limb deficiencies (ULDs) necessitates reliable outcome measures to track functional progress and prosthetic control during child development.
  • Current assessment tools may not adequately capture the nuances of functional abilities and prosthetic integration in children with ULDs.

Purpose of the Study:

  • To systematically review and critically appraise existing instruments for assessing upper limb function in children with ULDs.
  • To identify the most psychometrically sound and feasible outcome measures for use in clinical practice and research settings.

Main Methods:

  • A systematic literature search was conducted across PubMed, Embase, CINAHL, and Scopus, adhering to PRISMA guidelines.
  • Studies evaluating instrument validity, reliability, and responsiveness in children (<18 years) with ULDs were included.
  • Multiple reviewers independently screened studies, extracted data, assessed risk of bias, and rated psychometric properties using the COSMIN methodology.

Main Results:

  • Nineteen reports describing 4 performance-based tests and 6 patient-reported outcome measures were included.
  • No single ideal outcome measure currently exists for pediatric ULDs.
  • The Assessment of Capacity for Myoelectric Control and Assisting Hand Assessment demonstrate the best feasibility and psychometrics for standardized observational assessment, particularly for myoelectric prostheses.
  • The Child Amputee Prosthetics Project-Functional Status Inventory is provisionally recommended as a parent-reported questionnaire, though revisions and reliability studies are needed.

Conclusions:

  • Existing outcome measures for pediatric ULDs require further development and validation.
  • The Assisting Hand Assessment and Assessment of Capacity for Myoelectric Control are the most promising observational tools.
  • Further research is needed to refine and validate parent-reported questionnaires for broader clinical implementation.