Related Experiment Video
Updated: Jun 15, 2025
Development of a Virtual Reality Assessment of Everyday Living Skills
Published on: April 23, 2014
Neuromodulation in the treatment of social cognition dysfunction in Schizophrenia: a systematic review
Marta Moura Neves1,2,3, Fabiana Ventura1,2,4, Nuno Madeira5,6,7
1Department of Psychiatry and Mental Health, Coimbra Local Health Unit, Coimbra, Portugal.
Background:
Deficits in social cognition are significant barriers to functional living for individuals with schizophrenia. Although these symptoms have garnered increasing research attention, an effective treatment remains elusive. This systematic review evaluates the use of neuromodulation techniques in treating social cognition deficits in schizophrenia.
Methods:
We conducted a literature search in MEDLINE/PubMed, Web of Science, The Cochrane Library, and Embase databases, adhering to PRISMA guidelines. We included randomized, sham-controlled trials, non-controlled and/or open-label trials that assessed the efficacy of neuromodulation in patients diagnosed with schizophrenia (as per the DSM-III or later editions, or ICD equivalents), aged over 18 years.
Results:
Thirteen papers (1 on ECT, 4 on rTMS, and 8 on tES), including 11 RCTs, met the inclusion criteria. Seven of the thirteen analyzed studies indicated improvements in certain domains of social cognition associated with neuromodulation treatments.
Conclusions:
Neuromodulation techniques improved some domains of social cognition in individuals with schizophrenia. Further research is required to develop robust treatment protocols with proven efficacy in improving social cognition.
More Related Videos
05:14Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
Published on: September 8, 2021
06:42Continuous Theta Burst Stimulation of the Posterior Medial Frontal Cortex to Experimentally Reduce Ideological Threat Responses
Published on: September 28, 2018
Related Concept Videos
01:30Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
01:27Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
01:30Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
01:29Biological Causes of Schizophrenia
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...