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eyeris: A flexible, extensible, and reproducible pupillometry preprocessing framework in R.
Shawn T Schwartz1,2,3,4,5, Haopei Yang1,2, Alice M Xue1,2,3,5
1Stanford University, Stanford, United States.
Biorxiv : the Preprint Server for Biology
|June 12, 2025
Summary
A new pupillometry preprocessing suite, eyeris, enhances research reproducibility. It offers a standardized, FAIR-compliant workflow for analyzing pupil data, improving cognitive and emotional state insights.
Area of Science:
- Cognitive Neuroscience
- Psychophysiology
- Biomedical Engineering
Background:
- Pupillometry offers non-invasive insights into cognitive and emotional processes.
- Existing pupillometry preprocessing lacks standardization and FAIR principles, hindering reproducibility.
- Established tools exist for fMRI and EEG, but not for pupillometry.
Purpose of the Study:
- To develop a standardized, FAIR-compliant pupillometry preprocessing suite.
- To enhance reproducibility in pupillometry research.
- To provide an intuitive, modular, and extensible solution.
Main Methods:
- Development of the eyeris pupillometry preprocessing suite.
- Implementation of a recommended preprocessing workflow.
- Integration of signal processing best practices for tonic and phasic pupillometry.
- Generation of interactive reports for quality control and data sharing.
Main Results:
- eyeris provides a comprehensive solution for pupillometry preprocessing.
- The suite promotes FAIR and open science practices.
- It ensures high-fidelity preprocessing for improved reproducibility.
Conclusions:
- eyeris offers a robust, transparent, and adaptive solution for pupillometry.
- The tool aims to significantly improve reproducibility in the field.
- Standardized preprocessing is crucial for advancing pupillometry research.
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