[Criteria for the activity of the pathologic process in multiple sclerosis (clinico-computer tomographic...

Eight patients with the clinical signs of disease exacerbation were examined using computer-aided tomography of the head with contrast intensification. In 4 patients with a clinical aggravation expressed in the appearance of new neurological symptoms the authors obtained an effect of contrast intensification. Routine examination of the zones of the white substance revealed drug accumulation in the zones of both subnormal and normal density. There was no drug cumulation in 4 patients whose clinical aggravation was connected with the previous neurological symptomatology. The data obtained are discussed.