Related Experiment Video
Updated: Jun 14, 2025

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Periorbital Necrotizing Fasciitis: Presentation to management
Vladimir Mégevand1, Jérôme Martineau1, Maria Baccaro2
1Department of Plastic, Reconstructive, and Aesthetic Surgery, Geneva University Hospitals, Geneva University, 1205, Geneva, Switzerland.
Periorbital necrotizing fasciitis is a severe infection requiring prompt recognition and surgical debridement. Reconstructive surgery, including cheek advancement flaps, offers good aesthetic and functional outcomes for affected patients.
Area of Science:
- Ophthalmology
- Plastic Surgery
- Infectious Diseases
Background:
- Periorbital necrotizing fasciitis is a rare, rapidly progressing infection with high morbidity and mortality.
- Early symptoms are nonspecific, delaying diagnosis and treatment.
- Standard management (aggressive debridement) is challenging in the periorbital region due to risks to vision and cosmesis.
Observation:
- An 85-year-old male presented with a suspected upper eyelid abscess and rapid clinical deterioration.
- The patient underwent two surgical debridements of the periorbital area.
- Reconstruction utilized a Mustardé cheek advancement flap and a full-thickness skin graft.
Findings:
- The patient experienced no surgical complications.
- Aesthetic and functional improvements were noted shortly after reconstruction.
- Successful reconstruction highlights the viability of advanced surgical techniques in complex cases.
Implications:
- Early recognition and debridement are critical for favorable outcomes in periorbital necrotizing fasciitis.
- Reconstructive surgery techniques, such as those employed, can achieve satisfactory cosmetic and functional results.
- This case underscores the importance of tailored surgical approaches for periorbital infections.
Related Concept Videos
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Acute Pancreatitis II: Clinical Manifestations and Management
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...

