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Updated: Jun 13, 2025

Investigating Migraine-Like Behavior Using Light Aversion in Mice
Published on: August 11, 2021
Daily light exposure habits of youth with migraine: A prospective pilot study
Carlyn Patterson Gentile1, Ryan Shah2, Blanca Marquez de Prado1
1Children's Hospital of Philadelphia.
Abstract:
Photophobia is a common symptom in youth with migraine, but it is unknown if it leads to light avoidant behavior, and if such behaviors worsen disease burden. We conducted a feasibility study between November and March 2024 measuring light exposure using wearable light logger pendants in 20 youth with migraine (10-21 years old) while migraine symptoms were tracked with a text-based daily diary. On average, participants received recommended light exposure during only 14.5% +/- SD 7.0 of daylight hours but were consistently below the recommended maximum light levels 3 hours prior to bed (77.5% +/- 21.6 of the time), and at night (99.1% +/- 2.9 of the time). Daily light exposure patterns that were phase shifted 60 minutes later in youth with chronic (compared to non-chronic) migraine. Measuring daily light exposure is feasible in pediatric populations with photophobia and reveals intriguing trends that warrant further study.
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