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Author Spotlight: Innovative Microneedle-Based Strategies for Enhanced Exosome Delivery and Stability
Published on: July 12, 2024
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Progressive microneedles for targeting and intelligent drug delivery
Jiaqi Li1, Qing Xia1, Shuwen Ma1
1Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Asian Journal of Pharmaceutical Sciences
|June 12, 2025
Summary
Microneedle-mediated drug delivery systems (MDDS) offer precise drug delivery. This review categorizes MDDS designs and discusses their applications, challenges, and future prospects for industrialization.
Area of Science:
- Biomedical Engineering
- Drug Delivery Systems
- Nanotechnology
Background:
- Microneedle-mediated drug delivery systems (MDDS) are increasingly utilized for targeted administration.
- Diverse drug release mechanisms are being developed for precise delivery.
- Applications extend from skin to internal organs.
Purpose of the Study:
- To review and categorize the design strategies of various MDDS.
- To elucidate the classification of MDDS into Level-Ⅰ and Level-Ⅱ based on carrier integration.
- To discuss the current applications and future potential of MDDS in drug delivery.
Main Methods:
- Literature review of reported MDDS.
- Categorization of MDDS based on the integration of nanoscale and microscale carriers.
- Analysis of design strategies and application trends.
Main Results:
- MDDS designs were categorized into Level-Ⅰ and Level-Ⅱ.
- Review covered diverse applications in targeted and intelligent drug delivery.
- Current status and future prospects were analyzed.
Conclusions:
- MDDS represent a growing field with innovative design concepts.
- Categorization aids in understanding MDDS complexity and potential.
- Further development is needed for industrialization and clinical translation.
