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Diarrhea, Weight Loss, and an Elevated Gastrin: A Case Report
Ryan G Alexander1, John C Cheville2, Geoffrey B Thompson3
1Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Antral G-cell hyperplasia can mimic Zollinger-Ellison syndrome (ZES). Diagnosis involves differentiating G-cell hyperplasia from ZES using stimulation tests and imaging, with antrectomy as a treatment for refractory cases.
Area of Science:
- Gastroenterology
- Endocrinology
- Surgical Pathology
Background:
- Hypergastrinemia with refractory symptoms can indicate Zollinger-Ellison syndrome (ZES).
- Antral G-cell hyperplasia shares similar symptoms but requires specific diagnostic differentiation.
- Previous Nissen fundoplication complicated the diagnostic workup.
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