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Medical-grade honey: its definition and refined standards
Linsey Jf Peters1,2, Juraj Majtan3,4,5, Dimitris Mossialos6,7
1Triticum Exploitatie bv, the Netherlands.
Journal of Wound Care
|June 12, 2025
Summary
Medical-grade honey (MGH) requires updated standards for safety and efficacy due to antibiotic resistance. Refined guidelines ensure secure, effective honey use in modern medicine, meeting new regulations.
Area of Science:
- Food Science
- Medical Microbiology
- Regulatory Science
Background:
- Increasing antibiotic resistance necessitates exploring alternative medical treatments.
- Honey's therapeutic potential is gaining traction in modern medicine.
- Existing medical-grade honey (MGH) criteria require updates due to evolving challenges.
Purpose of the Study:
- To redefine medical-grade honey (MGH) and its essential criteria.
- To address challenges in honey authenticity and new medical device regulations.
- To ensure the safety and efficacy of honey used in medical applications.
Main Methods:
- Review and synthesis of current MGH standards.
- Analysis of new European Union Medical Device Regulation impacts.
- Proposal of refined criteria for MGH production and quality.
Main Results:
- Established refined criteria for MGH: organic production, gamma sterilization, clinical safety, production standards, and physicochemical properties.
- Emphasized the need for proven biological activity (antimicrobial, antioxidant) in MGH.
- Highlighted regulatory shifts and increased investment requirements.
Conclusions:
- Revised MGH guidelines ensure secure and effective medical use of honey.
- MGH plays a vital role in modern healthcare, particularly against antibiotic resistance.
- Adherence to updated standards and regulations is crucial for MGH efficacy.
