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Home Monitoring in Interstitial Lung Disease: Protocol for a Real-World Observational Study.

Marium Naqvi^1,2, Rebecca Borton³, Sarah Lines⁴

¹Department of Respiratory Medicine, Guy's and St Thomas Hospitals NHS Trust, London, United Kingdom.

JMIR Research Protocols

|June 12, 2025

Summary

Home monitoring for interstitial lung diseases (ILDs) shows promise for improving patient care. This approach aims to reduce hospital visits and tests, enhancing quality of life for those with ILD.

Keywords:

home monitoring interstitial lung disease multicenter observational study real-world remote monitoring spirometry

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Area of Science:

Pulmonary Medicine
Digital Health
Patient Monitoring

Background:

Interstitial lung diseases (ILDs) cause progressive breathlessness and reduced quality of life (QoL).
Acute exacerbations of ILDs lead to hospitalizations, increased costs, and high mortality.
Current standard care involves frequent in-person clinic visits, posing management challenges due to disease heterogeneity.

Purpose of the Study:

To evaluate the safety, effectiveness, and acceptability of home monitoring for patients with ILD.
To assess the impact of remote monitoring on disease management and patient outcomes.
To compare home monitoring with standard care in a real-world setting.

Main Methods:

A 12-month prospective study involving patients with ILD.
Utilizing handheld spirometers, pulse oximeters, and the patientMpower electronic health app for data collection.
Participants perform weekly spirometry and pulse oximetry, with quarterly patient-reported outcome measures.

Main Results:

186 patients enrolled by January 2024, with ongoing 12-month monitoring.
Data collection initiated in March 2022, with results anticipated by the end of 2025.
Home monitoring data is available to clinicians in real-time for disease and treatment assessment.

Conclusions:

Home monitoring is hypothesized to be safe, effective, and acceptable for ILD patients.
Anticipated outcome includes a 50% reduction in routine pulmonary function tests and clinic visits.
This approach offers a potential alternative to traditional in-person consultations for ILD management.