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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Monkeypox Presenting as an Isolated Finger Infection: A Case Report.

Yasmine Soubra1, Anirudh Sudarshan2, Amanda C Seymour2

  • 1Texas A&M College of Medicine, Houston, Texas.

JBJS Case Connector
|June 12, 2025
PubMed
Summary
This summary is machine-generated.

This case highlights monkeypox mimicking a bacterial infection in an HIV patient. Early recognition of monkeypox is crucial to prevent unnecessary surgical interventions.

Keywords:
abscesshandlocal wound caremonkeypoxmpoxnon-operativepresentationsymptomviralviruseswound

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Area of Science:

  • Infectious Diseases
  • Dermatology
  • Virology

Background:

  • Monkeypox (Mpox) can present with atypical symptoms.
  • Human immunodeficiency virus (HIV) may influence disease presentation.
  • Early diagnosis of viral infections is critical for appropriate management.

Purpose of the Study:

  • To describe an unusual case of monkeypox presenting as an isolated finger abscess.
  • To emphasize the importance of considering viral etiologies in unexplained skin lesions.
  • To highlight the diagnostic challenges in early-stage monkeypox.

Main Methods:

  • Case report of a 50-year-old male with HIV.
  • Initial presentation with an isolated dorsal index finger abscess.
  • Surgical debridement, histopathology, and polymerase chain reaction (PCR) for diagnosis.
  • Clinical follow-up and wound management.

Main Results:

  • Surgical pathology revealed poxvirus features, but no pus was initially found.
  • Subsequent development of generalized pustules confirmed as monkeypox via PCR.
  • The surgical site deteriorated, requiring a second debridement.
  • The finger lesion healed within 3 months with local wound care, preserving function.

Conclusions:

  • Monkeypox can initially mimic a bacterial abscess, delaying diagnosis.
  • This case underscores the need for vigilance in recognizing early, non-vesicular monkeypox signs.
  • Timely diagnosis and appropriate management can prevent unnecessary surgical procedures.