Related Experiment Video
Updated: Jun 14, 2025
Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
Published on: May 22, 2020
α-Fe Nanoparticles and Multiwalled Carbon Nanotubes Composite with Improved Photothermal Conversion Efficiency for
Ihtisham Ahmad Butt1, Peinan Yin1, Naihan Chen1
1School of Mechanics and Aerospace Engineering, State Key Laboratory of Structural Analysis, Optimization and CAE Software for Industrial Equipment, Dalian University of Technology, Dalian 116024, China.
None:
The efficiency of photothermal therapy based on conventional Fe3O4 nanoparticles (NPs) is limited due to their low absorption in the near-infrared (NIR) region. To surmount this obstacle, α-Fe nanoparticles/multiwalled carbon nanotubes (MWCNTs) composite is synthesized by incipient wetness impregnation (IWI). Due to improved extinction and heat generation mechanism (plasmons/electrons thermalization) of metallic Fe NPs with in nanocomposite structure, the photothermal conversion efficiency of Fe/MWCNTs composite is 87.98% (content: 60 μg/mL, 808 nm at power density of 1 W/cm2), which is highest among the previously reported Fe3O4 and other carbon-based nanostructures. The HaCaT cell viability after 72 h of coculturing is more than 91%, indicating the good biocompatibility of nanocomposite. The viability of B16-F10 melanoma cells is only 9.78% (808 nm laser irradiation for 15 min at 0.33 W/cm2), demonstrating the potential for hands-on applications.
