Surgical and Perioperative Advances for Patients With Locally Advanced Non-Small Cell Lung Cancer

Locally advanced non-small cell lung cancer (NSCLC) is primarily treated with multimodality therapy, which has undergone significant advancements over the years. Recently, the management of resectable NSCLC has evolved to provide patients more effective and tolerable options to prevent disease recurrence and increase rates of cure. In addition to surgical and screening advances, the use of tailored neoadjuvant, perioperative, and adjuvant therapies after resection has played a pivotal role. Innovations in surgical techniques and perioperative care, with a focus on precision medicine, have expanded the eligibility of patients for curative surgery. These advancements have been shown to improve patient outcomes by reducing both morbidity and mortality. This manuscript outlines the developments in the treatment of locally advanced NSCLC.