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Origins and functions of microbiome rhythms
Silke Kiessling1, Shuaitong Liu2, Dirk Haller3
1Faculty of Health and Biomedical Science, University of Surrey, 388 Stag Hill Campus, 17 GU27XH Guildford, UK.
Cell Host & Microbe
|June 12, 2025
Summary
Daily rhythms in gut microbiota impact host health. Understanding these diurnal oscillations is key to comprehending host-microbiota interactions and their role in metabolism and immunity.
Area of Science:
- Microbiology
- Circadian Biology
- Host-Microbe Interactions
Background:
- Daily oscillations in gut microbiota composition and function are increasingly recognized as vital for host-microbiota interactions.
- These diurnal rhythms influence host physiology, immunity, and metabolism.
- The gut microbiota is a critical factor in overall host health.
Purpose of the Study:
- To summarize the features of microbiota that exhibit diurnal rhythms.
- To explore the development and impact of these rhythms on host biology.
- To highlight the relevance of microbiota rhythmicity to human health and disease.
Main Methods:
- Review and synthesis of existing literature on microbiota oscillations.
- Focus on intrinsic and extrinsic factors regulating microbiota rhythms.
- Analysis of the roles of microbiota rhythmicity in host physiology, immunity, and metabolism.
Main Results:
- Microbiota composition and function exhibit significant daily oscillations.
- These rhythms are influenced by both internal host factors and external environmental cues.
- Microbiota rhythmicity plays multifaceted roles in host metabolic and immune functions.
Conclusions:
- Understanding the origins and functions of microbiota rhythms is crucial for circadian biology.
- Microbiota rhythmicity is a critical determinant of host health and disease.
- Further research into microbiota oscillations can lead to novel therapeutic strategies.
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