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Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
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  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Cancer Therapy (excl. Chemotherapy And Radiation Therapy)
  11. Systematic Double Reading For Oncological Pet/ct Scans: Insights From A Prospective Multicentre Study In 678 Patients.
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Cancer Therapy (excl. Chemotherapy And Radiation Therapy)
  11. Systematic Double Reading For Oncological Pet/ct Scans: Insights From A Prospective Multicentre Study In 678 Patients.

Related Experiment Video

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

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Systematic double reading for oncological PET/CT scans: insights from a prospective multicentre study in 678 patients.

Fabrice Gutman1,2, Didier Poncin1, Renaud Guedec-Ghelfi3

  • 1Hôpital Paul D'Egine, Champigny, France.

EJNMMI Reports
|June 12, 2025

View abstract on PubMed

Summary
This summary is machine-generated.

Systematic double reading of PET/CT reports identifies minor and rare impactful errors, improving accuracy in oncology. This process is crucial for reliable staging, restaging, and therapy monitoring in PET imaging.

Keywords:
Diagnostic errorsDouble readingOncologyPET/CT

More Related Videos

Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules
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Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules

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Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis
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Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis

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Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis
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Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis

Published on: October 25, 2024

354

Area of Science:

  • Nuclear Medicine
  • Radiology
  • Oncology

Background:

  • The increasing use of PET/CT in oncology for staging, restaging, and therapy monitoring, alongside the rise of theranostics, has led to higher workloads in PET facilities.
  • This increased demand raises concerns regarding the accuracy and reliability of PET/CT reports.

Purpose of the Study:

  • To prospectively evaluate the frequency and nature of errors in PET/CT reports.
  • To assess the effectiveness of a double-reading protocol in identifying and correcting these errors.

Main Methods:

  • A prospective study involving double reading of PET/CT scans ([18F]FDG, [18F]Choline, [18F]Dopa, [18F]PSMA) conducted between May and June 2024.
  • Independent review by a second reader, with a third reader consulted for consensus on significant changes.
  • Data collection on report changes (minor vs. impactful), reader confidence, diagnostic hypotheses, and potential influencing factors.

    • Main Results:

    • Changes were noted in 17% of PET reports, with impactful changes being rare (e.g., 5/20 in therapy monitoring, 2 major changes in staging/restaging).
    • Most changes involved phrasing/formatting (59%), laterality (10%), or target lesions not affecting TNM staging (29%).
    • No significant correlation was found between report changes and factors like reading timing, indication, prior scans, request clarity, reader experience, tracer type, or patient BMI.

    Conclusions:

    • Systematic double reading is effective in identifying and correcting both minor and rare impactful errors in PET/CT reports.
    • No specific predictive factors for error occurrence were identified, underscoring the necessity of a systematic approach to double reading.