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ECG Signal Analysis for Detection and Diagnosis of Post-Traumatic Stress Disorder: Leveraging Deep Learning and
Parisa Ebrahimpour Moghaddam Tasouj1, Gökhan Soysal2, Osman Eroğul3
1Biomedical Device Technology, Vocational School of Health Services, Ankara Medipol University, Ankara 06050, Turkey.
Diagnostics (Basel, Switzerland)
|June 13, 2025
Summary
Artificial intelligence using electrocardiogram (ECG) signals can detect post-traumatic stress disorder (PTSD). Deep learning models, particularly ResNet50, achieved over 94% accuracy, showing promise for non-invasive PTSD diagnosis.
Area of Science:
- Computational neuroscience
- Medical informatics
- Cardiovascular signal processing
Background:
- Post-traumatic stress disorder (PTSD) is a critical mental health condition with potential cardiovascular complications.
- Early and accurate diagnosis of PTSD is essential for effective treatment.
- Current diagnostic methods may be invasive or time-consuming.
Purpose of the Study:
- To develop and evaluate an artificial intelligence (AI) system for PTSD detection using electrocardiogram (ECG) signals.
- To compare the performance of deep learning (DL) models with traditional machine learning (ML) classifiers.
- To investigate the impact of ECG signal segment length on classification accuracy.
Main Methods:
- ECG signals were converted into time-frequency images using Continuous Wavelet Transform (CWT).
- Deep learning models (AlexNet, GoogLeNet, ResNet50) and traditional ML classifiers were employed.
- Performance was evaluated using various segment lengths (5s, 10s, 15s, 20s).
Main Results:
- ResNet50 achieved the highest accuracy (94.92%) with a 5-second ECG segment.
- Deep learning models significantly outperformed traditional ML approaches.
- The Area Under the Curve (AUC) for ResNet50 reached 0.99, indicating high diagnostic capability.
Conclusions:
- CNN-based models using ECG time-frequency representations show high accuracy for PTSD classification.
- Shorter ECG signal segments (5s) yield optimal performance.
- This AI-driven approach offers a promising non-invasive tool for PTSD diagnostic support.

