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Related Concept Videos

Obesity01:24

Obesity

416
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
416
Assessment of the Cardiovascular System I: Subjective Data01:23

Assessment of the Cardiovascular System I: Subjective Data

293
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
293
Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

523
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
523
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

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Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
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Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

69
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
69
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

4.0K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
4.0K
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. Chronotype, Lifestyles, And Anthropometric And Biochemical Indices For Cardiovascular Risk Assessment Among Obese Individuals.
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. Chronotype, Lifestyles, And Anthropometric And Biochemical Indices For Cardiovascular Risk Assessment Among Obese Individuals.

Related Experiment Video

Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome
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Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome

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Chronotype, Lifestyles, and Anthropometric and Biochemical Indices for Cardiovascular Risk Assessment Among Obese Individuals.

Margarida Rabaça Alexandre1, Rui Poínhos1,2, Cri-O Group3

  • 1Faculty of Nutrition and Food Sciences, University of Porto, 4150-180 Porto, Portugal.

Nutrients
|June 13, 2025

View abstract on PubMed

Summary
This summary is machine-generated.

Male sex, evening chronotype, and poor sleep quality are linked to worse cardiometabolic health in obese individuals. Integrating behavioral and circadian factors can improve cardiovascular risk assessment for severe obesity.

Keywords:
cardiovascular riskchronotypenutritionobesity

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Related Experiment Videos

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Area of Science:

  • Cardiology
  • Metabolic Health
  • Behavioral Science

Background:

  • Obesity significantly contributes to cardiovascular disease (CVD).
  • Traditional CVD risk assessment may not fully capture metabolic health influences from behavior and circadian rhythms.
  • Factors like chronotype, physical activity, sleep, eating speed, and breakfast habits are increasingly linked to cardiometabolic outcomes.

Purpose of the Study:

  • To investigate the associations between behavioral and circadian factors and anthropometric/biochemical markers of cardiovascular risk.
  • To evaluate these associations in obese individuals undergoing bariatric surgery evaluations.

Main Methods:

  • A cross-sectional study of 286 obese adults (mean BMI 42.5 kg/m²).
  • Assessed chronotype, sleep quality (Pittsburgh Sleep Quality Index), physical activity, eating speed, and breakfast skipping.
physical exercise
  • Measured cardiovascular risk markers including waist-to-hip ratio (WHR), A Body Shape Index (ABSI), atherogenic index of plasma (AIP), triglyceride-glucose index (TyG), and HOMA-IR.

    • Main Results:

    • Men showed higher WHR, ABSI, HOMA-IR, TyG, and AIP.
    • Evening chronotype correlated with higher insulin and HOMA-IR.
    • Poor sleep quality was linked to increased body fat mass, total cholesterol, and LDL cholesterol.
    • Faster eating speed associated with larger waist circumference and greater skeletal muscle mass.

    Conclusions:

    • Male sex, evening chronotype, and poor sleep quality are associated with adverse cardiometabolic profiles in severe obesity.
    • These behavioral and circadian factors are important considerations for cardiovascular risk assessment.
    • Findings support integrating these elements into comprehensive risk evaluation strategies.