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Biomedical And Clinical Sciences
Oncology And Carcinogenesis
Predictive And Prognostic Markers
The Influence Of Dietary Factors On Melanoma Development And Progression: A Comprehensive Review.

Home
Research Domains
Biomedical And Clinical Sciences
Oncology And Carcinogenesis
Predictive And Prognostic Markers
The Influence Of Dietary Factors On Melanoma Development And Progression: A Comprehensive Review.

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The Influence of Dietary Factors on Melanoma Development and Progression: A Comprehensive Review.

Abigail E Watson¹, Nabiha Yusuf²

¹College of Medicine, Florida State University, Tallahassee, FL 32306, USA.

|June 13, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

Dietary factors like polyunsaturated fatty acids (PUFAs) and antioxidants may protect against melanoma by reducing inflammation. Diet also impacts the gut microbiome, influencing melanoma progression and treatment response.

Keywords:

diet inflammation melanoma oxidative stress

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Area of Science:

Dermatology and Nutritional Science
Oncology
Immunology

Background:

Melanoma incidence is rising globally, with ultraviolet (UV) radiation as a primary risk factor.
Emerging evidence suggests diet significantly influences melanoma risk, progression, and treatment.
Understanding these dietary links is crucial for developing new prevention and management strategies.

Purpose of the Study:

To comprehensively review the impact of dietary components on melanoma pathogenesis.
To explore the roles of fats, vitamins, minerals, antioxidants, bioactive compounds, and the gut microbiome.
To identify potential nutritional strategies for melanoma prevention and treatment.

Main Methods:

Literature review of existing studies on diet and melanoma.

Analysis of research on specific dietary components (PUFAs, antioxidants, etc.).

Examination of the gut microbiome's role in melanoma and its interaction with diet.

Main Results:

Diets rich in PUFAs, antioxidants, and plant-based compounds may offer protection against melanoma.
These dietary factors can modulate oxidative stress, inflammation, and immune responses.
Dietary patterns influence gut microbiome composition, affecting melanoma progression and immunotherapy efficacy.

Conclusions:

Dietary interventions show promise for melanoma prevention and management.
The gut microbiome is a key mediator of diet's effects on melanoma.
Further large-scale studies are needed to establish definitive nutritional guidelines for melanoma.