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Difference Between Walking Parameters During 6 Min Walk Test Before and After Abdominal Surgery in Colorectal Cancer
Nikolina Santek1,2, Sanja Langer3, Iva Kirac4
1Department of Rheumatology, Physical Medicine and Rehabilitation, Sestre Milosrdnice UHC, 10000 Zagreb, Croatia.
Cancers
|June 13, 2025
Summary
The 6-minute walk test (6MWT) reveals higher heart rates post-surgery for colorectal cancer patients. Overweight and obese individuals showed the most significant increases in heart rate during the 6MWT after surgery.
Area of Science:
- Cardiology
- Oncology
- Exercise Physiology
Background:
- Colorectal cancer necessitates surgical intervention, making pre-surgical fitness assessment crucial.
- Cardiopulmonary exercise testing, including the 6-minute walk test (6MWT), objectively evaluates patient fitness before surgery.
- Assessing cardiorespiratory fitness aids in optimizing surgical outcomes and recovery.
Purpose of the Study:
- To evaluate changes in cardiorespiratory fitness using the 6-minute walk test (6MWT) in colorectal cancer patients before and after surgery.
- To identify factors influencing post-surgical recovery and fitness levels.
- To analyze differences in 6MWT performance based on demographics and body mass index.
Main Methods:
- Seventy-two colorectal cancer patients awaiting surgery participated.
- The 6-minute walk test (6MWT) was administered two days before and seven days after surgery.
- Quality of life and recovery questionnaires were completed pre- and post-operatively.
Main Results:
- Statistically significant differences were observed in walk distance between men and women (p=0.02).
- Patient age correlated significantly with the number of steps taken during the 6MWT (p=0.02).
- Body mass index influenced average and maximal heart rates during the 6MWT (p=0.00 and p=0.04, respectively).
Conclusions:
- Post-operative heart rates during the 6-minute walk test (6MWT) were elevated compared to pre-operative levels.
- Overweight and obese participants exhibited particularly higher heart rates in the post-operative period.
- The 6MWT is a valuable tool for monitoring cardiorespiratory fitness changes following colorectal cancer surgery.

