Related Experiment Video
Updated: Aug 16, 2026
Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring
Published on: April 3, 2015
Non-Invasive Hemodynamic Monitoring in Transcatheter Aortic Valve Implantation
Thorald Stolte1, Janarthanan Sathananthan2, Jakob Johannes Reichl1
1Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, 4031 Basel, Switzerland.
Insights
The ClearSight® system, a non-invasive method, showed lower hemodynamic values and poor correlation compared to invasive monitoring during Transcatheter Aortic Valve Implantation (TAVI). This suggests limitations in its current use for TAVI hemodynamic assessment.
Area of Science:
- Cardiovascular Medicine
- Medical Devices
- Hemodynamics
Background:
- Aortic stenosis (AS) is common in elderly patients, often treated with Transcatheter Aortic Valve Implantation (TAVI).
- Current hemodynamic monitoring during TAVI is invasive.
- The ClearSight® Finger Cuff system offers a non-invasive alternative.
Purpose of the Study:
- To compare the reliability and feasibility of non-invasive hemodynamic monitoring (ClearSight®) with traditional invasive methods during TAVI.
Main Methods:
- Prospective observational study of 50 patients undergoing elective TAVI.
- Invasive hemodynamics via arterial/pigtail catheters; non-invasive via ClearSight®.
- Data collected on baseline, procedural, and 30-day outcomes.
Main Results:
- Non-invasive CO, CI, and SV were consistently lower than invasive measurements (p<0.05 for CO and CI).
- Non-invasive blood pressure was lower than invasive readings.
- Low correlation (Mean percentage error 52%) between non-invasive and invasive measurements.
Conclusions:
- The ClearSight® system yielded lower absolute hemodynamic values compared to invasive methods.
- Low correlation was observed between non-invasive and invasive measurements pre- and post-TAVI.
- Current non-invasive monitoring may not be reliable for TAVI hemodynamic assessment.
Abstract:
Background/Objectives: Aortic valve stenosis (AS) is a prevalent cardiovascular condition among elderly patients frequently treated with Transcatheter Aortic Valve Implantation (TAVI). Traditional hemodynamic monitoring during TAVI relies on invasive methods. The ClearSight® Finger Cuff system offers a non-invasive alternative for continuous hemodynamic monitoring. To compare the reliability and feasibility of non-invasive hemodynamic monitoring with traditional invasive hemodynamic monitoring during TAVI procedures. Methods: In this prospective observational study, patients undergoing elective TAVI were recruited from two tertiary hospitals between March and August 2023. Invasive hemodynamic measurements were obtained using arterial and pigtail catheters, with a subset undergoing right heart catheterization. Non-invasive measurements were captured using the ClearSight® system. Data on baseline characteristics, procedural details, and 30-day follow-up outcomes were collected. Results: The study cohort comprised 50 patients (median age 82 years (IQR 78.0, 85.8), 50% female). Non-invasive measurements of cardiac output (CO), cardiac index (CI), and stroke volume (SV) were consistently lower than invasive measurements (CO: 4.1 vs. 4.8 L/min, p = 0.03; CI: 2.2 vs. 2.7 L/min/m2, p = 0.01, SV: 66 vs. 77 mL, p = 0.25). Non-invasive blood pressure readings were lower than invasive radial and aortic measurements before and after TAVI. Correlation of non- and invasive measurements was low but similar before and after TAVI (Mean percentage error of 52%). Conclusions: The ClearSight® system provided lower absolute values for all evaluated hemodynamic parameters as well as low correlation compared to traditional methods pre- as well as post-interventional.
