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Related Concept Videos

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

77
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
77
Modeling in Therapy01:26

Modeling in Therapy

61
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
61
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

50
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
50
Operant Conditioning Intervention01:24

Operant Conditioning Intervention

52
Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...
52
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  11. Children And Adolescents With Co-occurring Attention-deficit/hyperactivity Disorder And Autism Spectrum Disorder: A Systematic Review Of Multimodal Interventions.
  1. Home
  3. Research Domains
  5. Psychology
  7. Applied And Developmental Psychology
  9. Child And Adolescent Development
  11. Children And Adolescents With Co-occurring Attention-deficit/hyperactivity Disorder And Autism Spectrum Disorder: A Systematic Review Of Multimodal Interventions.

Related Experiment Video

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos
05:32

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos

Published on: December 7, 2018

8.9K

Children and Adolescents with Co-Occurring Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder: A Systematic Review of Multimodal Interventions.

Carmela De Domenico1, Angelo Alito2, Giulia Leonardi3

  • 1I.R.C.C.S. Centro Neurolesi Bonino Pulejo, 98124 Messina, Italy.

Journal of Clinical Medicine
|June 13, 2025

View abstract on PubMed

Summary
This summary is machine-generated.
Keywords:
Autism spectrum disorderattention deficit disorder with hyperactivitybehavior therapydrug therapy

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Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

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A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research

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Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos
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Methylphenidate (MPH) and atomoxetine (ATX) show effectiveness in managing Attention-deficit/hyperactivity Disorder (ADHD) core symptoms in children with Autism Spectrum Disorder (ASD). Non-pharmacological interventions require further research.

Area of Science:

  • Neurodevelopmental Disorders
  • Pediatric Psychiatry
  • Clinical Psychology

Background:

  • Co-occurrence of Attention-deficit/hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) is common.
  • This dual diagnosis frequently leads to diminished adaptive functioning.
  • There is a significant need for effective interventions in this population.

Purpose of the Study:

  • To systematically review pharmacological and non-pharmacological interventions for children with co-occurring ADHD and ASD.
  • To evaluate the efficacy and safety of these interventions.
  • To identify gaps in current research for this underserved group.

Main Methods:

  • Systematic literature search of PubMed, Embase, and Web of Science databases.
  • Inclusion of pilot studies and RCTs in participants under 18 with diagnosed ADHD and ASD.
intervention
psychopharmacology
treatment
  • Quality assessment using Newcastle Ottawa Scale and Cochrane Risk of Bias Tools.

    • Main Results:

    • Thirty-two studies were included, predominantly (87.5%) on pharmacological treatments.
    • Methylphenidate (MPH) and atomoxetine (ATX) demonstrated efficacy in reducing ADHD core symptoms.
    • Atomoxetine (ATX) also showed benefits for stereotyped behaviors and social withdrawal, with higher adverse event (AE) withdrawals than MPH.
    • Non-pharmacological interventions (virtual reality, digital platforms, etc.) showed promise for emotion recognition, behavioral regulation, attention, and social functioning.

    Conclusions:

    • Methylphenidate (MPH) and atomoxetine (ATX) appear relatively safe and effective for hyperactivity-impulsivity symptoms in children with co-occurring ADHD and ASD.
    • Evidence for non-pharmacological interventions is limited.
    • Further research is necessary to establish the therapeutic potential of non-pharmacological approaches.