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Updated: Jun 16, 2025
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Controlled Photoredox Ring-Opening Polymerization of O-Carboxyanhydrides Mediated by Ni/Zn Complexes
Published on: November 21, 2017
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Unsaturated Macrolactones from Renewable Feedstocks: Synthesis, Ring-Opening Polymerization and Application Prospects
Ilya Nifant'ev1,2, Anna Afanaseva1,3, Alexander Vinogradov1
1A.V. Topchiev Institute of Petrochemical Synthesis RAS, 29 Leninsky Pr., 119991 Moscow, Russia.
International Journal of Molecular Sciences
|June 13, 2025
Summary
This review explores synthesizing unsaturated macrolactones (UMs) using metathesis catalysis. This catalytic method offers an atom-economy alternative to traditional organochemical routes and aligns with Green Chemistry principles.
Area of Science:
- Organic Chemistry
- Polymer Science
- Catalysis
Background:
- Unsaturated macrolactones (UMs) possess reactive ester and C=C bonds, making them valuable synthetic targets.
- Naturally occurring UMs are scarce, necessitating efficient synthetic strategies.
- Advances in metathesis catalysis have revolutionized UM synthesis.
Purpose of the Study:
- To review the application of ring-closing metathesis in UM synthesis.
- To compare catalytic metathesis with conventional organochemical methods for UM production.
- To discuss the use of UMs in unsaturated polyester synthesis and applications.
Main Methods:
- Ring-closing metathesis catalyzed by Ruthenium (Ru) and Group 6 metal complexes.
- Comparison of catalytic and organochemical synthetic approaches.
- Exploration of unsaturated polyester synthesis from UMs.
Main Results:
- Metathesis catalysis provides an atom-economy route to UMs.
- Ruthenium and Group 6 metal catalysts are effective for UM synthesis.
- UMs can be utilized in creating functional unsaturated polyesters.
Conclusions:
- Metathesis catalysis is a powerful and sustainable tool for synthesizing unsaturated macrolactones.
- The use of renewable feedstocks in UM synthesis aligns with Green Chemistry.
- Synthesized unsaturated polyesters show promise for practical applications.
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