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Circulating Monocytes Contribute to Erythrocyte Clearance in Polycythemia Vera

Marina D Borges1, Izabela F Paes1, Daniela P Leonardo1

  • 1Laboratory of Hemoglobin and Genome, Hematology and Hemotherapy Center, University of Campinas (UNICAMP), Campinas 13083-878, SP, Brazil.

International Journal of Molecular Sciences
|June 13, 2025
PubMed
Summary

Monocytes in polycythemia vera (PV) patients clear red blood cells and influence erythroid cell differentiation, similar to macrophages. This study reveals their role in PV erythrophagocytosis and erythropoiesis.

Keywords:
erythroblastic islanderythrophagocytosismacrophagesmyeloproliferative syndrome

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