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Review on 3D Printing Filaments Used in Fused Deposition Modeling Method for Dermatological Preparations
Yong Li Chan1, Riyanto Teguh Widodo1, Long Chiau Ming2,3
1Department of Pharmaceutical Technology, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Molecules (Basel, Switzerland)
|June 13, 2025
Summary
Three-dimensional printing, specifically Fused Deposition Modeling (FDM), enables personalized dermatological drug delivery using various polymers. This technology offers improved treatment efficacy and patient compliance for skin conditions.
Area of Science:
- Biomedical Engineering
- Materials Science
- Dermatology
Background:
- Three-dimensional printing (3D printing) offers novel approaches to drug delivery.
- Fused Deposition Modeling (FDM) is a key 3D printing technique for customized formulations.
- Dermatological drug delivery faces challenges in precision and patient compliance.
Purpose of the Study:
- To review polymers used in FDM for dermatological drug delivery.
- To analyze the advantages and limitations of these polymers.
- To assess the potential of FDM in personalized dermatological treatments.
Main Methods:
- Literature review of polymers like PLA, PVA, PEG, and PCL for FDM applications.
- Analysis of polymer properties influencing drug release and stability.
- Evaluation of FDM-customized systems for dermatological use.
Main Results:
- Polymers such as PLA, PVA, PEG, and PCL offer unique properties for tailored drug release.
- FDM allows for the creation of patient-specific dermatological drug delivery systems.
- Challenges include polymer moisture sensitivity and mechanical brittleness.
Conclusions:
- FDM technology holds significant promise for revolutionizing dermatological drug delivery.
- Optimized materials and advanced printing techniques are crucial for future advancements.
- Personalized 3D-printed systems can enhance therapeutic outcomes and patient quality of life.
