Three Cases of Lyme Carditis and a Review of Management

Ryan F Coughlin1, Anne Fox2, Erin Underriner3

  • 1Department of Emergency Medicine, Yale University School of Medicine, New Haven, CT, USA.

Insights

Lyme carditis, a complication of Lyme disease, can cause various heart blocks. Prompt diagnosis and treatment with antibiotics like ceftriaxone and doxycycline are crucial for recovery and preventing permanent heart issues.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Emergency Medicine

Background:

  • Lyme carditis, caused by Borrelia burgdorferi, affects 1-10% of untreated Lyme disease patients.
  • It can manifest with varying degrees of atrioventricular (AV) block.
  • Diagnosis can be challenging due to non-specific symptoms and lack of clear tick exposure history.

Purpose of the Study:

  • To review cases of Lyme carditis presenting to an emergency department.
  • To highlight the variable presentations of Lyme carditis, including different types of AV block.
  • To emphasize the importance of prompt recognition and management in endemic areas.

Main Methods:

  • Retrospective review of three emergency department cases of Lyme carditis.
  • Analysis of patient demographics, symptoms, cardiac findings (AV block degrees), and treatment outcomes.
  • Diagnostic confirmation through Lyme antibody testing and Western blot.

Main Results:

  • Three patients presented with first-degree, Type 2 second-degree, and complete heart block.
  • All patients received intravenous ceftriaxone, with two also treated with doxycycline.
  • All cases showed resolution of AV block following antibiotic treatment, with one requiring temporary pacing.

Conclusions:

  • Lyme carditis presents with diverse cardiac manifestations, including significant AV block.
  • Early diagnosis and antibiotic treatment (ceftriaxone, doxycycline) are effective in resolving Lyme carditis.
  • High clinical suspicion is vital in emergency settings to avoid unnecessary interventions like permanent pacemakers.

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