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Published on: September 28, 2019
Management and Clinical Outcomes of Pancreaticoduodenal Injuries at a Tertiary Care Centre in Southern India
Lokeshwaran Ayyasamy1, Senthilkumaran Govindaraj Raman1, Sudhagar Rengasamy1
1Department of Surgical Gastroenterology & GI Oncology, Thanjavur Medical College, Thanjavur, IND.
Insights
Diagnosing pancreaticoduodenal injuries requires high suspicion due to their location. Delayed treatment of these blunt trauma injuries significantly increases patient morbidity and mortality.
Area of Science:
- Trauma Surgery
- Surgical Gastroenterology
- Abdominal Trauma
Background:
- Pancreaticoduodenal injuries present diagnostic challenges due to their retroperitoneal location.
- Early diagnosis and prompt management are crucial to mitigate morbidity and mortality.
- Delayed presentation of these injuries is associated with increased adverse outcomes.
Purpose of the Study:
- To analyze the demographics, presentation, grading, management, morbidity, and mortality of pancreaticoduodenal injuries.
- To identify factors influencing outcomes in patients with pancreaticoduodenal injuries.
Main Methods:
- An ambispective study involving 31 patients over a five-year period (October 2019 - October 2024).
- Data collected included patient demographics, injury mechanism, clinical status on arrival, injury grade, treatment received, and postoperative outcomes.
Main Results:
- The majority of patients were male (93.5%) and sustained blunt trauma (83.8%).
- Postoperative morbidity was 32%, and mortality was approximately 7%.
- Delayed admission (>48 hours) was significantly associated with increased postoperative morbidity (p = 0.029).
- Nonoperative management was successful in five high-grade (Grade 4) injuries; one Grade 5 injury required a Whipple procedure.
Conclusions:
- A high index of suspicion is essential for diagnosing pancreaticoduodenal injuries.
- Delayed diagnosis and treatment adversely affect patient morbidity and mortality.
- Conservative management with serial monitoring may be considered for selected high-grade injuries in specialized centers.
Objective:
Pancreaticoduodenal injuries are complex, and early diagnosis is often missed due to their retroperitoneal location. Serial clinical monitoring and imaging are essential for the management of these injuries. Morbidity and mortality increase in patients with delayed presentation. The aim of this study is to analyse the demography, mode of presentation, grading, management, morbidity and mortality of these injuries at our centre.
Methods:
This is an ambispective study conducted on 31 patients over a period of five years, between October 1, 2019 and October 15, 2024.
Results:
Most patients were male (93.5%). Blunt trauma was associated with the majority of cases (83.8%). Twenty-nine patients were hemodynamically stable on arrival at the trauma/emergency ward. Postoperative morbidity was around 32% in our study, whereas mortality was approximately 7%. Nonoperative management was followed in five cases of high-grade (Grade 4) pancreatic injury. One patient with Grade 5 pancreaticoduodenal injury underwent an emergency Whipple procedure. In our study, postoperative morbidity associated with delayed admission beyond 48 hours from the time of injury was statistically significant (p = 0.029).
Conclusion:
A high index of suspicion is needed in every case. Delayed diagnosis and treatment negatively impact morbidity and mortality. In selected cases of high-grade pancreatic injuries, conservative management with serial follow-up and imaging can be considered at a well-equipped tertiary care centre.
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