Efficacy of External Siddha Pharmacotherapy for Giant Acrochordon: A Case Report

Giant acrochordons, commonly referred to as skin tags, are benign, pedunculated lesions often linked to conditions such as obesity, diabetes, and metabolic syndrome. While these lesions are generally harmless, they can lead to discomfort or cosmetic concerns, prompting individuals to seek treatment. Traditional methods, including excision and cryotherapy, are frequently employed but come with certain risks. This study explores the use of Pachaieruvai, a traditional Siddha medicine, as an alternative treatment option. The subject of this report was a 50-year-old male who had a large skin tag on his gluteal region that had been growing for 15 years. Opting for Pachaieruvai over surgery, he applied the topical preparation for 10 days. Remarkably, the lesion was completely resolved within 15 days, and follow-up evaluations at two weeks, three weeks, and six months showed no recurrence or complications. Pachaieruvai comprises five ingredients recognized for their cytotoxic properties, including arsenic trioxide and copper sulfate, which may assist in targeting abnormal cell growth. However, the study's small sample size, absence of controlled trials, and potential safety concerns regarding arsenic necessitate further research to validate its efficacy and establish standardized treatment protocols.