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Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
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Relationship Between Child Turcotte Pugh (CTP) Score and Esophageal Varices (EV) Among Sudanese Cirrhotic Patients in

Eltype Elsiddig1, Alaaeldeen Alhassan2, Osman Amir3

  • 1Al Hasahisa Teaching Hospital Al Hasahisa Sudan.

Health Science Reports
|June 13, 2025
PubMed

Insights

Cirrhotic patients with higher Child Turcotte Pugh (CTP) scores have advanced esophageal varices (EV). Regular endoscopy is recommended for CTP B and C patients to monitor for EV progression.

Area of Science:

  • Hepatology
  • Gastroenterology
  • Internal Medicine

Background:

  • Esophageal varices (EV) are a critical complication of cirrhosis, necessitating early diagnosis.
  • Current guidelines recommend pre-bleeding diagnosis of EV in all cirrhosis patients.
  • The Child Turcotte Pugh (CTP) class is a recognized prognostic indicator for variceal bleeding in cirrhosis.

Purpose of the Study:

  • To investigate the relationship between Child Turcotte Pugh (CTP) scores and the presence and grade of esophageal varices (EV) in patients with cirrhosis.

Main Methods:

  • A descriptive cross-sectional study included 67 cirrhotic patients from November 2020 to November 2021.
  • Data collected included demographics, clinical history, presentations, ultrasound findings, and laboratory tests.
  • Child Turcotte Pugh (CTP) and Model for End-Stage Liver Disease (MELD) scores were calculated, and upper gastrointestinal (UGI) endoscopy was performed to grade EV.

Main Results:

  • The majority of patients (46.3%) presented with Grade III EV.
  • Higher CTP class (CTP-C) and MELD scores (≥40) were significantly associated with advanced EV grades (III and IV) (p < 0.0001).
  • Biomarkers including hyperbilirubinemia, hypoalbuminemia, and elevated INR levels also showed significant association with advanced EV grades (p < 0.0001).

Conclusions:

  • Cirrhotic patients with elevated MELD and CTP scores exhibit a higher likelihood of advanced esophageal varices.
  • The study recommends increased surveillance with esophagogastroduodenoscopy (EGD) for patients classified as Child Pugh B and C due to the increased risk of advanced EV.
Abstract

Keywords:
Child Pugh scoreSudanesecirrhosisesophageal varices

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