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  11. Efficacy Of Wound Healing (vrana Ropana) After Lobuloplasty With And Without Panchavalkala Extract. 5% W/v - Randomized Control Trial.
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  7. Traditional, Complementary And Integrative Medicine
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  11. Efficacy Of Wound Healing (vrana Ropana) After Lobuloplasty With And Without Panchavalkala Extract. 5% W/v - Randomized Control Trial.

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Efficacy of wound healing (Vrana Ropana) after lobuloplasty with and without panchavalkala extract. 5% w/v - randomized control trial.

Adnan F Chhatriwala1, Lakshmi Shetty1, Arati Dubewar2

  • 1Departments of Oral and Maxillofacial Surgery, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth. Pimpri Pune, Maharashtra, India.

National Journal of Maxillofacial Surgery
|June 13, 2025

View abstract on PubMed

Summary
This summary is machine-generated.

This study found that the herbal extract panchavalkala significantly improved wound healing (vrana ropana) in lobuloplasty patients, reducing infection and speeding debridement. It offers a promising alternative to conventional treatments.

Keywords:
Bilateral lobuloplastyear lobe cleftpanchavalkala

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Area of Science:

  • Ayurvedic Medicine
  • Oral and Maxillofacial Surgery
  • Wound Healing Research

Background:

  • Alternative Indian medicine, particularly herbal remedies, is gaining attention for therapeutic applications.
  • Panchavalkala, an herbal extract from five tree barks, is traditionally recognized for its wound healing properties (vrana ropana).

Purpose of the Study:

  • To evaluate the efficacy of 5% w/v panchavalkala extract in promoting wound healing after lobuloplasty.
  • To compare the wound healing outcomes with and without the use of panchavalkala extract in a randomized controlled trial.

Main Methods:

  • A double-blinded randomized controlled trial was conducted on 25 patients undergoing bilateral lobuloplasty.
  • Patients were treated with either 5% w/v panchavalkala extract or a conventional ointment (neosporin) on different surgical sites.
  • Wound healing was assessed using criteria such as slough, swelling, redness, pain, discharge, tenderness, and malodor at various time points.

    • Main Results:

    • After 15 days, panchavalkala extract showed statistically significant improvements in reducing slough (P = .012), swelling (P = .021), and redness (P = .039).
    • No significant differences were observed between groups for pain, discharge, tenderness, or malodor at the 15-day interval.

    Conclusions:

    • The 5% w/v panchavalkala extract effectively reduces clinical signs of infection and accelerates wound debridement.
    • Panchavalkala extract demonstrates potential as an effective agent for wound healing (vrana ropana) in the maxillofacial region, serving as a viable alternative to allopathic ointments.