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Combining 3D Magnetic Force Actuator and Multi-Functional Fluorescence Imaging to Study Nucleus Mechanobiology
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Mechanosensitive nuclear checkpoint: nuclear envelope as a sensor of chromosomal instability and driver of cell fate

Chenyang Ji1, Junwei Chen1, Fuxiang Wei1

  • 1Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Laboratory for Cellular Biomechanics and Regenerative Medicine, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, 430074, China.

Mechanobiology in Medicine
|June 13, 2025
PubMed

Keywords:
Cell cycleChromatinGene expressionMechanosensitive checkpointNuclear envelope

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