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Clinical and Radiographic Evaluation of Effect of Ellagic Acid on Osseointegration Around Dental Implants: An
Mehjubah1, Ghanta Chaitanya2, Syeda Tawkhira Tabasum3
1Department of Periodontics, Government Dental College and Hospital, Vijayawada, Andhra Pradesh, India.
Objective:
To evaluate the clinical and radiographic effects of ellagic acid on osseointegration around dental implants.
Materials And Methods:
A total of 60 patients, aged between 25 and 55 years, requiring dental implants, were designated for the study. They were randomly divided into two sects: The experimental group (30 patients) received dental implants with ellagic acid, and the control group (30 patients) received dental implants without ellagic acid. The peri-implant pocket depth, implant stability, and gingival index were recorded. Radiographic analysis was conducted to measure bone density and marginal bone loss around the implants at 3-, 6-, and 12-months post-implantation.
Results:
The experimental group showed significantly higher implant stability and bone density compared to the control group at all time points (P < 0.05). The peri-implant pocket depth and gingival index were lower in the experimental group, indicating better periodontal health. Radiographically, the experimental group demonstrated less marginal bone loss compared to the control group.
Conclusion:
Ellagic acid enhances osseointegration around dental implants, resulting in improved clinical outcomes and reduced marginal bone loss.

