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Updated: Jun 14, 2026

High Content Screening in Neurodegenerative Diseases
Published on: January 6, 2012
Showcasing the Comprehensive Understanding of Cellular Profiling and Human Neurophysiology
Deepali Jadhav1, Ranjit S Ambad2
1Department of Physiology, Datta Meghe College of Pharmacy, Datta Meghe Institute of Higher Education and Research, Sawangi (M), Wardha, Maharashtra, India.
Abstract:
Cellular profiling and human neurophysiology are significant points of convergence between molecular, biological, and neural science. Cellular phenotyping refers to the breaking down of cells to understand their molecular and functional characteristics. Human neurophysiology, in contrast, is re-concerned with function and centers on the human neural system. This work offers a systematic view of these domains and intends to disentangle how these domains interact in understanding neural processes, cell responses, and diseases. This research uses modern approaches, including single-cell RNA sequencing and electrophysiological approaches, to explore cell heterogeneity and neurophysiological phenotypes in human specimens. The overlying cross-sectional approach allows for the accurate determination of cell subtypes and their involvement in specific neurophysiological functions, thus facilitating the design of highly specific treatment plans.

