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Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
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Ewing sarcoma of the clavicle: a case report
Whitney Fuqua1, Whitney Graff2, Lauren Tollefson3
1Life University, Marietta, GA.
The Journal of the Canadian Chiropractic Association
|June 13, 2025
Summary
This case study highlights an unusual clavicle location for Ewing sarcoma, emphasizing how delayed diagnosis impacts patient care and outcomes. Early detection and treatment are crucial for managing this rare bone cancer.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Ewing sarcoma is a rare bone cancer typically affecting children and young adults.
- Unusual locations, such as the clavicle, can delay diagnosis.
- Patient care pathways are critical for timely intervention.
Purpose of the Study:
- To report a rare case of primary Ewing sarcoma in the clavicle.
- To illustrate the diagnostic challenges and consequences of delayed diagnosis.
- To underscore the importance of prompt patient care and oncologic referral.
Main Methods:
- Case report of a 23-year-old male with a left clavicle mass.
- Initial and repeat radiographic evaluation.
- Advanced imaging including CT, MRI, and PET-CT.
- Biopsy for histopathological confirmation.
- Oncologic management including chemotherapy and radiation.
Main Results:
- Initial radiographs were negative, delaying diagnosis by approximately one year.
- Repeat imaging revealed aggressive bone destruction and a soft tissue mass.
- Metastatic disease was identified.
- Biopsy confirmed primary Ewing sarcoma.
- Initial treatment led to remission, but recurrence occurred two years later.
Conclusions:
- The clavicle is an unusual site for Ewing sarcoma, posing diagnostic challenges.
- Delayed diagnosis significantly impacts prognosis and treatment outcomes.
- Multidisciplinary care, including timely imaging and oncologic consultation, is essential for improving patient survival rates.
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