Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Skin tests for chymopapain allergy.

J A McCulloch, W D Canham, J Dolovich

    Annals of Allergy
    |October 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Skin prick tests reliably predict allergic reactions to chymopapain (CP) injections. A positive test indicates a contraindication for CP therapy, preventing adverse events in patients.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Differential co-occurrence analysis: a method to extract ecological modules from clinical microbiome data.

    mSystems·2026
    Same author

    Impact of mutations in hVISA isolates on decreased susceptibility to vancomycin, through population analyses profile - area under curve (PAP-AUC).

    Diagnostic microbiology and infectious disease·2019
    Same author

    Outpatient discolysis with chymopapain.

    Orthopedics·2014
    Same author

    Assessment and treatment of asthma.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Investigation and management of rhinitis.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Otitis media in children.

    Canadian family physician Medecin de famille canadien·2011

    Area of Science:

    • Allergy and Immunology
    • Pharmacology
    • Neurosurgery

    Background:

    • Chymopapain (CP) is an enzyme used therapeutically.
    • Assessing patient sensitivity to CP before administration is crucial.

    Purpose of the Study:

    • To evaluate the efficacy of skin prick tests in predicting allergic reactions to therapeutic chymopapain (CP).

    Main Methods:

    • Skin prick tests using chymopapain (CP) solution (10 mg/mL) were performed before therapeutic CP injections.
    • Patient reactions to CP injections were recorded based on skin test results.

    Main Results:

    • Only 1% (3/232) of patients with negative skin tests reacted to CP injection.
    • A significant 83% (5/6) of patients with positive skin tests experienced reactions to CP injection.

    Related Experiment Videos

    Conclusions:

    • Positive chymopapain (CP) skin tests are a strong indicator of potential allergic reactions.
    • A positive CP skin test should be considered a contraindication for therapeutic CP injection to ensure patient safety.