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Microbial Biosensors01:17

Microbial Biosensors

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Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
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  1. Home
  3. Ultrathin Boron Nanosheets: A Novel Fluorescent Sensor For Sensitive And Selective Detection Of Fe3+ And Ascorbic Acid.
  1. Home
  3. Ultrathin Boron Nanosheets: A Novel Fluorescent Sensor For Sensitive And Selective Detection Of Fe3+ And Ascorbic Acid.

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Ultrathin boron nanosheets: a novel fluorescent sensor for sensitive and selective detection of Fe3+ and ascorbic

Tao Guo1, Jiu Xu1, Yating Guo2

  • 1College of Ecological Environment and Urban Construction, Fujian University of Technology, Fuzhou 350118, PR China.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
|June 13, 2025

View abstract on PubMed

Summary
This summary is machine-generated.

This study introduces ultrathin boron nanosheets (Ultrathin BNSs) as a novel fluorescent probe for detecting iron(III) (Fe3+) and ascorbic acid (AA). The sensor shows high sensitivity and selectivity, with potential applications in biological and environmental monitoring.

Keywords:
AADetectionFe(3+)Fluorescent probeSensorUltrathin boron nanosheets

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Analytical Chemistry

Background:

  • Iron(III) (Fe3+) and ascorbic acid (AA) play crucial roles in human health.
  • Efficient and sensitive detection methods for Fe3+ and AA are critical.
  • Existing fluorescent probes often have limitations in sensitivity or selectivity.

Purpose of the Study:

  • To develop a novel fluorescent probe for the sensitive detection of Fe3+ and AA.
  • To synthesize and characterize ultrathin boron nanosheets (Ultrathin BNSs) for sensing applications.
  • To evaluate the performance of Ultrathin BNSs as a nanoprobe in human serum.

Main Methods:

  • Synthesis of Ultrathin BNSs via ultrasound-assisted liquid-phase exfoliation.
  • Investigation of the fluorescence "on-off-on" mechanism triggered by Fe3+ and AA.
  • Quantification of Fe3+ and AA using Ultrathin BNSs as a fluorescent nanoprobe.

    • Main Results:

    • Ultrathin BNSs exhibit a fluorescence quantum yield of 6.8% and low cytotoxicity.
    • A selective "on-off-on" fluorescence response was observed for Fe3+ and AA detection.
    • Linear detection ranges were established from 0.2 to 150 µM for Fe3+ and 1.5 to 110 µM for AA.
    • Limits of detection were as low as 0.2 µM for Fe3+ and 1.5 µM for AA.
    • Successful application of the sensor for AA detection in human serum.

    Conclusions:

    • Ultrathin BNSs offer a promising platform for developing sensitive and selective fluorescent sensors.
    • The developed sensor demonstrates superior performance compared to existing methods.
    • This approach provides a new strategy for rapid, cost-effective biosensing and environmental monitoring.