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ChatGPT-4o in Enhancing Informed Consent in Pediatric Surgical Practice
Catarina Barros Azevedo1, Ana Sofia Martinho2, Inês Braga2
1Department of Pediatric, ULS Alto Ave, 4835-044, Guimarães, Portugal.
Journal of Pediatric Surgery
|June 13, 2025
Summary
Artificial intelligence (AI) significantly improves pediatric informed consent (IC) documents. Both legal representatives and surgeons preferred AI-generated ICs, boosting satisfaction and quality in pediatric care.
Area of Science:
- Medical Informatics
- Artificial Intelligence in Healthcare
- Pediatric Surgery
Background:
- Informed consent (IC) is crucial for high-quality healthcare but faces implementation challenges.
- Artificial intelligence (AI) shows potential for improving medical practices.
- This study investigates AI's role in generating personalized IC documents.
Purpose of the Study:
- To assess ChatGPT-4o's performance in creating personalized informed consent (IC) documents.
- To evaluate pediatric surgeons' and patients'/legal representatives' satisfaction with AI-generated ICs.
Main Methods:
- A cross-sectional, observational study compared original ICs with AI-generated ICs (GPT-4o) for pediatric surgical patients.
- Quality was assessed by patients/legal representatives and pediatric surgeons using eight parameters.
Main Results:
- AI-generated ICs (AI-IC) were rated higher by legal representatives across all parameters (p<0.05).
- Pediatric surgeons also preferred AI-IC, except for conciseness (p=0.06).
- 82.6% of legal representatives and 87.5% of surgeons showed a statistically significant preference for AI-IC.
Conclusions:
- AI enhances satisfaction with the informed consent process in pediatric care.
- AI-generated ICs have the potential to improve the overall quality of informed consent.
- Further research on AI platforms in medicine is essential.

