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Reversed Remodeling Unveils Mitral Annular Disjunction.
Tess Calcagno1, Joseph El Roumi1, Christopher Black1
1Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
JACC. Case Reports
|June 13, 2025
Summary
Mitral annular disjunction (MAD) is often linked to cardiomyopathy. This case shows how cardiac MRI can reveal MAD in nonischemic cardiomyopathy (NICM) as the heart condition improves.
Area of Science:
- Cardiology
- Cardiac Imaging
- Structural Heart Disease
Background:
- Mitral annular disjunction (MAD) is a recognized abnormality associated with mitral valve prolapse (MVP) and cardiomyopathy.
- Its role in nonischemic cardiomyopathy (NICM) requires further elucidation.
Keywords:
arrhythmogenic mitral valve diseaseatrial fibrillationcardiac MRIcardiac imagingcardiac remodelingextracellular volume fraction (ECV)guideline-directed medical therapy (GDMT)heart failurelate gadolinium enhancement (LGE)left ventricular dysfunctionmitral annular disjunction (MAD)mitral regurgitationmitral valve prolapse (MVP)myocardial fibrosismyocardial scarnonischemic cardiomyopathy (NICM)reverse remodelingrisk stratificationsudden cardiac death (SCD)ventricular arrhythmiaMore Related Videos
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