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Increased Circulating Interleukin Concentrations in Type 2 Diabetes: A Systematic Review and Meta-Analysis

Chang Cao1,2, Jing Yuan1, Elizabeth R Gilbert3

  • 1Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.

Obesity Reviews : an Official Journal of the International Association for the Study of Obesity
|June 14, 2025
PubMed
Summary

Patients with Type 2 diabetes exhibit elevated levels of circulating interleukins (IL-4, IL-6, IL-17, IL-18) compared to healthy individuals. This meta-analysis confirms a systemic inflammatory response associated with Type 2 diabetes.

Keywords:
Type 2 diabetesbody mass indexinflammationinterleukinsmeta‐analysis

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