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Related Experiment Videos

Acute hypothyroidism in a 3 year old.

U MacFadyen, B P O'Malley, P G Swift

    Archives of Disease in Childhood
    |September 1, 1985
    PubMed
    Summary

    A young child experienced rapid onset of hypothyroidism symptoms like fatigue and joint swelling. This case highlights that primary hypothyroidism can develop quickly, even in toddlers.

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    Area of Science:

    • Pediatrics
    • Endocrinology
    • Immunology

    Background:

    • Primary hypothyroidism is a common endocrine disorder, often developing gradually.
    • Autoimmune processes are frequently implicated in pediatric hypothyroidism.

    Observation:

    • A 3-year-old girl presented with a rapid onset of symptoms including lethargy, constipation, and joint swelling over three weeks.
    • Clinical investigation revealed primary hypothyroidism accompanied by immunological markers, specifically thyroglobulin antibodies.

    Findings:

    • The patient was diagnosed with primary hypothyroidism with evidence of autoimmune activity.
    • Thyroxine treatment was initiated, and reassessment confirmed persistent hypothyroidism several months later.

    Implications:

    • This case underscores that primary hypothyroidism can manifest as an acute or rapid-onset condition in children.
    • Early recognition of rapid-onset hypothyroidism is crucial for timely diagnosis and management in pediatric patients.

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