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Patient-reported outcomes in patients with paroxysmal nocturnal hemoglobinuria treated with crovalimab and approved C5 inhibitors in the phase III COMMODORE 2 and 1 studies

  • 1Department of Oncology, Hematology, Hemostaseology and Stem Cell Transplantation, University Hospital RWTH Aachen, Aachen, Germany.
  • 2Centre for Integrated Oncology (CIO), Aachen, Bonn, Cologne, Düsseldorf (ABCD), Germany.
  • 3Department of Hematology, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking, People's Republic of China.
  • 4Institute of Hematology and Blood Transfusion, Prague, Czech Republic.
  • 5Hematology Service, Hospital Clínico San Carlos, Madrid, Spain.
  • 6Department of Hematology, Tokyo Medical University, Tokyo, Japan.
  • 7Department of Haematological Medicine, King's College Hospital, London, UK.
  • 8National Institute for Health Research and Wellcome King's Clinical Research Facility and King's College London, London, UK.
  • 9Medical Center "Ok!Clinic+" of International Institute of Clinical Research LLC, Kyiv, Ukraine.
  • 10Institute of Hematology and Transfusiology, National Academy of Medical Science, Kyiv, Ukraine.
  • 11Department of Hematology, Ege University, Izmir, Turkey.
  • 12Division of Hematology, Hospital A Beneficência Portuguesa, São Paulo, Brazil.
  • 13Institute of Transfusion Medicine, University of Ulm, Ulm, Germany.
  • 14Institute of Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Transfusion Service Baden-Württemberg-Hessen und University Hospital Ulm, Ulm, Germany.
  • 15Department of Haematology, University Hospital Saint-Luc, Brussels, Belgium.
  • 16Department of Hematology and Oncology, Graduate School of Medicine, Faculty of Medicine, Osaka University, Suita, Japan.
  • 17Genentech, Inc., South San Francisco, CA, USA.
  • 18Genentech, Inc., South San Francisco, CA, USA. bgentile@gmail.com.
  • 19F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • 20Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
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June 14, 2025

No abstract available