Comment on the clinicopathological analysis of thyroid carcinomas with the RET and NTRK fusion genes: characterization for genetic analysis in thyroidology

Ilker Sengul ^1,2, Demet Sengul ³

¹Division of Endocrine Surgery, Giresun University Faculty of Medicine, TR28100, Giresun, Turkey. ilker.sengul.52@gmail.com.
²Department of General Surgery, Giresun University Faculty of Medicine, TR28100, Giresun, Turkey. ilker.sengul.52@gmail.com.
³Department of Pathology, Giresun University Faculty of Medicine, TR28100, Giresun, Turkey.

Virchows Archiv : an international journal of pathology +

June 14, 2025

No abstract available

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Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

Comment on the clinicopathological analysis of thyroid carcinomas with the RET and NTRK fusion genes: characterization for genetic analysis in thyroidology

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Comment on the clinicopathological analysis of thyroid carcinomas with the RET and NTRK fusion genes: characterization for genetic analysis in thyroidology

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