Related Experiment Video
Updated: Jun 16, 2025
A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
Increased Allergic Rhinitis Prevalence and Symptom Severity in Patients With Irritable Bowel Syndrome.
María Cuende-Estévez1, Hind Hussein1, Fedrica Pia1
1Department of Chronic Diseases and Metabolism (CHROMETA), Center for Intestinal Neuroimmune Interactions, Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven, Leuven, Belgium.
Patients with irritable bowel syndrome (IBS) have a significantly higher risk of allergic rhinitis (AR). This combination negatively impacts quality of life and may involve cross-reactivity between airborne and food allergens.
Area of Science:
- Immunology
- Gastroenterology
- Allergology
Background:
- Irritable bowel syndrome (IBS) is linked to increased risks of airway and allergic diseases.
- The connection between allergic rhinitis (AR) and IBS is not well understood.
- Investigating airway issues in IBS patients and potential antigen cross-reactivity is crucial.
Purpose of the Study:
- To understand airway complications in IBS patients.
- To evaluate airborne and dietary antigen cross-reactivity in patients with both IBS and AR.
Main Methods:
- 287 participants (54 healthy, 232 IBS patients) completed questionnaires.
- Assessed upper airway symptom severity and AR prevalence.
- Rome IV criteria used for IBS diagnosis.
Main Results:
- IBS patients had a threefold higher risk of AR compared to controls.
- IBS patients with AR reported poorer sleep, mood, and satisfaction.
- 47% of IBS+AR patients experienced IBS symptoms due to food mimicking aeroallergens.
Conclusions:
- IBS patients have a higher incidence of AR, worsening quality of life.
- Evidence suggests cross-reactivity between aeroallergens and food antigens in IBS+AR patients.
More Related Videos
10:37Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
Published on: November 30, 2016
03:40Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
Published on: December 20, 2024
Related Concept Videos
01:17Irritable Bowel Syndrome I: Introduction
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
01:30Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
01:30Irritable Bowel Syndrome III: Medical and Nursing Management
01:17Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
01:17Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
01:30Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...