Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Urinary Tract Calculi III: Medical Management

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Landscape of Prostate Tumour Methylation.

Cancer discovery·2026

Same author

A Multidisciplinary Approach to Prevention and Treatment of Late Genitourinary Adverse Events After Radiotherapy for Prostate Cancer.

European urology·2026

Same author

NCCN Guidelines® Insights: Prostate Cancer, Version 5.2026.

Journal of the National Comprehensive Cancer Network : JNCCN·2026

Same author

Local Salvage Therapy Alone for Local Recurrence of Prostate Cancer After Radiotherapy: A Systematic Review and Meta-Analysis.

JAMA oncology·2026

Same author

Extended Follow-up from the Stereotactic Body Radiotherapy for High-risk Localized Carcinoma of the Prostate (SHARP) Consortium: Updated Analysis of 440 Patients.

European urology oncology·2026

Same author

Cost-effectiveness of an artificial intelligence predictive model for guiding androgen deprivation therapy in intermediate-risk prostate cancer.

JNCI cancer spectrum·2026

Same journal

Integrative Medicine for Breast Cancer Survivors.

Seminars in radiation oncology·2026

Same journal

Integrative Oncology Approaches for Gastrointestinal Symptoms and Risk Reduction in Patients With Digestive Tract Cancers.

Seminars in radiation oncology·2026

Same journal

Integrative Oncology and Radiation Therapy: An Essential Evolution.

Seminars in radiation oncology·2026

Same journal

Clinical Trials of Integrative Oncology Interventions for Radiation Therapy: Emerging Evidence and Opportunities.

Seminars in radiation oncology·2026

Same journal

Nonpharmacologic Approaches for Pain Management in Patients With Cancer Treated With Radiation Therapy.

Seminars in radiation oncology·2026

Same journal

Integrative Therapies for Radiation-Related Toxicities in Hematological Malignancies.

Seminars in radiation oncology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 1, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

The Evolving Management of Radiorecurrent Prostate Cancer.

Jacob Pozin¹, Menal Bhandari², Luca Valle³

¹Department of Internal Medicine, Loyola University Medical Center, Maywood, IL.

Seminars in Radiation Oncology

|June 14, 2025

Summary

This summary is machine-generated.

Detecting prostate cancer recurrence after radiation therapy is easier with new imaging. Salvage re-irradiation offers a chance for cure and delays hormone therapy, but requires careful consideration of risks and benefits.

More Related Videos

Focal Laser Ablation of Prostate Cancer: An Office Procedure

Focal Laser Ablation of Prostate Cancer: An Office Procedure

Published on: March 30, 2021

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

Related Experiment Videos

Last Updated: May 1, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

Focal Laser Ablation of Prostate Cancer: An Office Procedure

Focal Laser Ablation of Prostate Cancer: An Office Procedure

Published on: March 30, 2021

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

Area of Science:

Oncology
Radiation Oncology
Medical Imaging

Background:

Prostate cancer recurrence after radiation therapy is increasingly detected with advanced imaging like PSMA PET/CT.
Optimal workup and management strategies for local radiorecurrence (LRR) are crucial.

Purpose of the Study:

To review the literature on identifying LRR post-radiation therapy.
To define the optimal workup for LRR detection.
To discuss management principles, focusing on salvage re-irradiation.

Main Methods:

A narrative review of existing literature and ongoing studies.
Focused on workup and treatment strategies for LRR.
Included analysis of imaging modalities and biopsy techniques.

Main Results:

Workup involves PSMA PET/CT, multiparametric MRI, and biopsy to confirm LRR extent.
Salvage re-irradiation options include SBRT, HDR brachytherapy, and LDR brachytherapy.
Salvage re-irradiation is a safe and effective option for potential cure and delaying ADT.

Conclusions:

Salvage re-irradiation provides a second chance for prostate cancer cure and can delay palliative androgen deprivation therapy (ADT).
Careful consideration of benefits versus risks is essential for patients with LRR.
Further research is needed to optimize re-irradiation parameters (volume, dose, fractionation).